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Press releases 2006

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Press releases are intended to journalists, analysts and investors.

Canadian Federal Court of Appeals rules in sanofi-aventis’ favor in the Canadian Plavix Notice of Compliance proceedings

December 28, 2006

Sanofi pasteur influenza vaccine production tops 170 million doses in 2006

December 20, 2006

Sanofi-aventis statement regarding U.S. FDA Joint Advisory Committee recommendation for Ketek® (telithromycin)

December 15, 2006

New organization announced for January 1st, 2007

December 14, 2006

Taxotere®-based regimens with Herceptin® in women with early-stage HER2-positive breast cancer demonstrate the highest reduction in the risk of death to date and provide a treatment option without anthracyclines

December 14, 2006

New study shows Clexane® / Lovenox® (enoxaparin sodium injection) is more effective than unfractionated heparin (UFH) for preventing the risk of venous thromboembolism (VTE) in patients with acute ischemic stroke

December 12, 2006

Idraparinux shows encouraging results in Van Gogh clinical trials program

December 10, 2006

Preliminary Injunction Against Apotex Upheld on Appeal

December 8, 2006

New data shows ACOMPLIA® (rimonabant) benefited patients with type 2 diabetes by improving blood sugar control, reducing weight and acting on other cardiometabolic risk factors

December 5, 2006

Sanofi-aventis receives pediatric exclusivity for AMBIEN® and AMBIEN® CR

November 29, 2006

Sanofi pasteur completes shipment of 50 million doses of influenza vaccine

November 27, 2006

Sanofi pasteur signs contract with U.S. government for stockpile of new type of H5N1 pre-pandemic vaccine

November 20, 2006

Sanofi-aventis, Innogenetics, and Inserm to collaborate on Alzheimer’s disease

November 13, 2006

Sweden grants reimbursement of Acomplia™ (rimonabant) for overweight patients with associated risk factors

November 10, 2006

Acomplia™ receives 1st marketing authorisation in the North American continent

November 9, 2006

First 9 months of 2006: Sales growth of 2.6% on a comparable basis - Adjusted EPS growth of 15.0%, or 7.5% excluding selected items

October 31, 2006

New Head of sanofi-aventis Communications Department

October 26, 2006

The commercial subsidiary of sanofi-aventis in France is presenting a reorganisation plan resulting in the loss of 504 posts

October 25, 2006

Sanofi-aventis objects to the recommendation of the German Federal Joint Committee (“Gemeinsamer Bundesausschuss” – “G-BA”) regarding Acomplia

October 18, 2006

Sanofi Pasteur H5N1 pre-pandemic vaccine neutralizes additional circulating H5N1 virus

October 18, 2006

Taxotere® receives U.S. FDA approval for the treatment of patients with head and neck cancer

October 18, 2006

Sanofi-aventis has sold its entire stake in Rhodia

October 17, 2006

Sanofi-aventis announces the sale of its stake in Rhodia

October 17, 2006

Positive interim efficacy results from large randomized adjuvant gastric cancer trial

October 13, 2006

Sanofi-aventis strengthens its commitment with the World Health Organization (WHO) to fight neglected tropical diseases

October 10, 2006

Childhood cancers: second call for projects "My Child Matters"

October 2, 2006

Sanofi-aventis and UCB sign a co-promotion agreement for Xyzal® in the United States

September 25, 2006

TAXOTERE® receives positive opinion from the Committee for Medicinal Products for Human Use (CHMP) recommending approval in the European Union for head and neck cancer

September 22, 2006

Sanofi pasteur broadens pandemic preparedness with first clinical trial of novel cell based H7N1 vaccine

September 19, 2006

Sanofi-aventis prevails in arbitration against Rhodia

September 13, 2006

New Head of sanofi-aventis Human Resources Department

September 11, 2006

European commission expands indication for PLAVIX® (clopidogrel bisulfate) offering new option for patients with most severe type of heart attack

September 7, 2006

Sanofi-aventis withdraws European application for marketing authorization for dronedarone (MULTAQ™) in the treatment of Atrial Fibrillation/Atrial Flutter

September 7, 2006

New clinical data show enoxaparin significantly reduces the risk of repeat heart attacks and stroke in patients undergoing percutaneous coronary intervention (PCI)

September 4, 2006

Preliminary injunction ordered in PLAVIX® patent infringement case - Apotex to halt sales of unauthorized generic

September 1, 2006

New trial date set for Lovenox® patent infringement suit

August 31, 2006

Sanofi-aventis receives a non approvable letter from the FDA for dronedarone (MULTAQ™) in the treatment of Atrial Fibrillation/Atrial Flutter - New filing expected during the first semester of 2008

August 31, 2006

FDA approves new indication for PLAVIX® (clopidogrel bisulfate) offering new option for patients with most severe type of heart attack

August 17, 2006

Motion filed for preliminary injunction in PLAVIX® patent infringement case

August 14, 2006

Trial date set for LOVENOX® patent infringement suit

August 10, 2006

Update regarding PLAVIX® patent infrigement case

August 8, 2006

Availability on-line of the Group’s interim report for the first half of 2006

August 4, 2006

First half of 2006: Sales growth of 7.7% on a reported basis and 4.5% on a comparable basis - Adjusted EPS growth of 32.9%, or 16.1% excluding selected items

August 2, 2006

PLAVIX® litigation settlement fails to receive antitrust clearance from states attorneys general

July 28, 2006

Sanofi-aventis responds to the emergency request for humanitarian aid to Lebanon

July 20, 2006

Sanofi-aventis and Taiho sign an agreement for the development and marketing of an oral anticancer agent: S-1

July 3, 2006

Sanofi-aventis announces update to KETEK® (telithromycin) U.S. prescribing information

June 29, 2006

Update on PLAVIX® litigation settlement

June 25, 2006

ACOMPLIA® (rimonabant) receives marketing authorisation in the European Union

June 21, 2006

New study shows insulin glargine (LANTUS®) as effective and better tolerated than the prandial insulin lispro in initiating insulin therapy in type 2 diabetes

June 13, 2006

New study shows an innovative mealtime insulin dosing algorithm may provide a safe and effective alternative to carbohydrate counting for patients with type 2 diabetes

June 10, 2006

Study findings presented on TAXOTERE® regimens in head and neck, lung and breast cancer

June 7, 2006

Studies evaluating ELOXATIN®-based regimens in gastrointestinal cancers presented at the 42nd annual meeting of the American Society of Clinical Oncology (ASCO)

June 5, 2006

Results of a meta-analysis show benefits of Taxotere® (docetaxel) regimens in patients with advanced non-small cell lung cancer (NSCLC)

June 3, 2006

General Meeting of Shareholders

June 1, 2006

New Eloxatin® and Taxotere® data in several tumor types to be presented at the annual meeting of the American Society of Clinical Oncology (ASCO)

May 30, 2006

Adjuvanted formulation of Sanofi Pasteur H5N1 pandemic influenza vaccine candidate demonstrates significant immune response

May 11, 2006

PLAVIX® (clopidogrel) launched in Japan

May 9, 2006

First quarter of 2006: Sales growth of 9.6% on a reported basis and 4.9% on a comparable basis. 52.8% growth in adjusted EPS and 19.8% excluding selected items.

May 5, 2006

Acomplia® (rimonabant) recommended for approval in the European Union

April 28, 2006

Transfer of all Japanese rimonabant rights to Sanofi-aventis

April 12, 2006

Appeals court rules in Sanofi-aventis’ favor in the U.S. Lovenox® (enoxaparin sodium) patent infringement case

April 10, 2006

Lantus®: publication of the LANMET study results

April 3, 2006

Filing of the 2005 U.S. Form 20-F and French ''Document de Référence''

March 31, 2006

Sanofi-aventis acquires 24.876% of Zentiva and becomes its largest shareholder

March 27, 2006

TAXOTERE® receives positive opinion from the Committee for Medicinal Products for Human Use recommending approval in the European Union for metastatic stomach cancer

March 24, 2006

TAXOTERE® receives U.S. FDA approval for use in advanced stomach cancer

March 23, 2006

Sanofi-aventis and Bristol-Myers Squibb announce agreement to settle U.S. Plavix® litigation with Apotex subject to certain conditions

March 21, 2006

Press release - Plavix®: Questions and Answers

March 21, 2006

Agreement between Sanofi-aventis and Roche to produce shikimic acid

March 16, 2006

New study furthers understanding of the role of dual antiplatelet therapy in the prevention of atherothrombotic events, including heart attack, stroke or cardiovascular death in broad population

March 12, 2006

Rescheduling of the trial date in the United States PLAVIX® litigation

February 28, 2006

Apidra® – A New Rapid-Acting Insulin Analog – is Now Available in the United States for Hyperglycemia in Adults with Type 2 and Type 1 Diabetes

February 28, 2006

Strong growth of 25.7% in 2005 adjusted EPS - Nearly 90% of synergies delivered by end 2005 - Dividend increased by 26.7%

February 24, 2006

Sanofi-aventis received from the FDA an approvable letter for rimonabant for weight management and a non approvable letter for smoking cessation

February 17, 2006

The Journal of the American Medical Association publishes the RIO-North America study

February 14, 2006

Sanofi-aventis voluntarily recalls 30 batches of enoxaparin syringes as a precautionary measure

February 10, 2006

Sanofi pasteur delivers more H5N1 vaccine for U.S. government pandemic initiatives

February 6, 2006

''My child matters'': launch of a mobilisation campaign against childhood cancer in emerging countries

January 31, 2006

Dynamic growth in 2005 full-year consolidated net sales: up 9.3% on a comparable basis - Excellent performance from vaccines: up 26.9% on a comparable basis - 2005 adjusted earnings guidance raised - Approval of Plavix® in Japan

January 30, 2006

Xaliproden: final results of the Xenox clinical trial announced

January 28, 2006

PLAVIX®: Sanofi-aventis statement

January 24, 2006

PLAVIX® approved in Japan

January 24, 2006

FDA grants priority review to PLAVIX® (clopidogrel bisulfate) supplemental new drug application (sNDA) for additional type of heart attack

January 18, 2006

Pfizer to purchase sanofi-aventis rights to EXUBERA® in application of change of control clauses

January 13, 2006

FDA issues a written request for pediatric studies for zolpidem

January 11, 2006